![]() These findings suggest that adjusting the neurite curvature offers a possible route to treating schizophrenic hallucinations. The next target cell can be another nerve cell, a muscle cell or a gland. ![]() ![]() Their job is to carry chemical signals (messages) from one neuron (nerve cell) to the next target cell. The neurite curvature also showed a correlation with a hallucination score (Pearson's r = 0.80, p = 1.8 × 10 -4), indicating that neurite structure is relevant to brain function. What are neurotransmitters Neurotransmitters are chemical messengers that your body can’t function without. In contrast to the control cases, the schizophrenia cases deviate upward from this correlation, exhibiting a 60% higher neurite curvature compared with the controls (p = 7.8 × 10 -4). ![]() The distribution profiles of neurite curvature of the control cases showed a trend depending on their age, resulting in an age-correlated decrease in the standard deviation of neurite curvature (Pearson's r = -0.80, p = 0.018). Schizophrenia usually develops during puberty through early adulthood and is suspected to interrupt brain development, but the degree of neural alteration remains unclear in schizophrenia.Ī new study, published in PLOS ONE, performed nanometer-scale three-dimensional analyses of post-mortem brain tissues of patients with schizophrenia and tissues from control patients by using synchrotron radiation nanotomography (nano-CT). ![]()
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